Functional Magnetic Resonance Imaging - Synthetic Aperture Magnetometry (fMRI-SAM) and Alzheimer's Disease
Not Applicable
Withdrawn
- Conditions
- Alzheimer's Disease
- Interventions
- Procedure: fMRI to detect MCI patients who will convert to Alzheimer's disease
- Registration Number
- NCT00412048
- Lead Sponsor
- University Hospital, Strasbourg, France
- Brief Summary
The aim of the protocol is to study the resting brain activation profile of 3 groups of people, using a new fMRI procedure, called fMRI-SAM. fMRI-SAM will be applied to 25 Alzheimer's disease (AD) patients, 25 patients suffering from amnestic - mild cognitive impairment (MCI) - a clinical picture which may be a prodromal form of AD - and 60 healthy controls. The first analysis of the data will search differences of brain activation profiles between the 3 groups. In the second step, the investigators will study the predictive value of fMRI-SAM to detect MCI patients who will later convert to AD.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- WITHDRAWN
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
Not provided
Exclusion Criteria
Not provided
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description ALZHEIMER DISEASE fMRI to detect MCI patients who will convert to Alzheimer's disease - MOLD COGNITIVE IMPAIRMENT fMRI to detect MCI patients who will convert to Alzheimer's disease - CONTROLS fMRI to detect MCI patients who will convert to Alzheimer's disease -
- Primary Outcome Measures
Name Time Method Comparing fMRI data between 3 groups of subjects: MCI, Alzheimer's disease and normal subjects 1, 5 years
- Secondary Outcome Measures
Name Time Method Follow-up of MCI patients at 6, 12 and 18 months to detect a conversion to Alzheimer's disease Prediction of Alzheimer's disease on fMRI data