G-CSF and PRP in Patients With Recurrent Implantation Failure

Phase 2

• Conditions: Infertility,Female
• Interventions: Drug: Granulocyte colony-stimulating factor and platelet-rich plasma group; Other: Control group

• Registration Number: NCT04411212
• Lead Sponsor: Riyadh Fertility and Reproductive Health center

Brief Summary

The aim of this randomized controlled trial is to determine whether granulocyte colony-stimulating factor and platelet-rich plasma can be used to enhance the IVF-ET outcomes in patients with recurrent implantation failure

Detailed Description

Not available

Study Timeline

• Status Verified: 2020-05
• Study First Submitted: 2020-05-27
• Study Start: 2020-05-28
• Study First Submitted QC: 2020-06-01
• Last Update Submitted: 2020-06-01
• Study First Posted: 2020-06-02
• Last Update Posted: 2020-06-02
• Primary Completion: 2020-12-31
• Study Completion: 2021-03-31

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: Female
• Target Recruitment: 112

Inclusion Criteria

• Patients with history of three or more unsuccessful IVF-ET cycles with at least 2 good quality embryos transferred

Exclusion Criteria

• Endometriosis
• Uterine anomalies
• Asherman syndrome

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Granulocyte colony-stimulating factor and platelet-rich plasma	Granulocyte colony-stimulating factor and platelet-rich plasma group	-
Control group	Control group	-

Primary Outcome Measures

Name	Time	Method
Clinical pregnancy rate	Five weeks after embryo transfer	Gestational sac detected by ultrasound examination

Trial Locations

Locations (1)

Riyadh Fertility and Reproductive Health center; 🇪🇬 Giza, Egypt