Open randomized comparative clinical study of local application of Prapunnatadi Lepa with Khadirvrushadi Lepa in management of Dadru with special reference to Tinea Corporis
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 62
- 试验地点
- 1
- 主要终点
- size of lesion
研究概览
简要总结
In slum areas people treat fungal infections only in monsoon. To treat the infections, they use
antifungal creams. There are certain antifungal creams that contain steroids. Long term use of such
creams causes resistance to the dermatophytes, causing Lichenification, Hyperkeratosis and Hypertrophy
of localized skin.
According to Ayurveda, Dadru being a Twakgat vyadhi, out of all the treatment modalities, Lepa
is one of the best types of local application and the most effective method of drug administration for
treating skin conditions, as it penetrates the deeper layers of skin. It is also readily available and
reasonably priced.
I therefore made the decision to research the impact of local applications of ‘Prapunnatadi Lepa’
and ‘Khadirvrushadi Lepa’ in Dadru with a focus on Tinea Corporis.
There are several Ayurvedic preparations for treating Dadru that can be used both internally and
externally. It is necessary to study and evaluate efficacy of these medications by scientific research.
As all the contents of Prapunnatadi Lepa are herbal in nature, they are cost effective and easily
available, proving beneficial to the society. Considering their ayurvedic properties they might even prove
useful in certain contagious skin diseases.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 80.00 Year(s)(—)
- 性别
- Female
入选标准
- •Age-18 to 80 years.
- •Sex – All genders
- •Patient with signs and symptoms of Dadru like Kandu, Pidika, Vaivarnya and mandala.
- •Understanding and willing to sign the informed consent form.
- •Area of lesion up to 25cm 2.
排除标准
- •Patient having skin lesion other than Dadru kushtha (Tinea corporis) like Eczema, psoriasis, urticaria etc.
- •Pregnancy and lactating mother.
- •K/C/O AIDS (HIV +ve), HbSAg +ve etc.
结局指标
主要结局
size of lesion
时间窗: 15 days
number of lesion (in specific area of body)
时间窗: 15 days
次要结局
- The symptoms of Dadru mentioned in text and practically observed will be assessed at each follow-up.(Kandu (Itching), Raga (Erythema), Pidaka (papule), Daha (burning).)
研究者
Aishwarya Yashwant Nalawade
APMs Ayurved Mahavidyalaya Sion Mumbai
