Improving Human Ovarian Transplantation

Early Phase 1

• Conditions: Fertility Preservation

• Registration Number: NCT00827476
• Lead Sponsor: Hadassah Medical Organization

Brief Summary

we will perform xenotransplantation and in vitro culture of ovarian tissue from patients undergoing ovarian cortex cryopreservation.

Detailed Description

Ovarian tissue is removed by laparoscopy and only in patients facing premature ovarian failure due to chemotherapy.Tissue for research will consist either of a small portion (\<10%) of the cortex for preservation for young women. another source of ovarian tissue for research will be obtained following consent from family of patients who have died of the disease and have previously frozen ovarian tissue.

Study Timeline

• Status Verified: 2009-01
• Study Start: 2009-01
• Study First Submitted: 2009-01-21
• Study First Submitted QC: 2009-01-21
• Last Update Submitted: 2009-01-21
• Study First Posted: 2009-01-22
• Last Update Posted: 2009-01-22
• Primary Completion: 2012-01
• Study Completion: 2015-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: Female
• Target Recruitment: 100

Inclusion Criteria

• tissue previously obtained

Exclusion Criteria

• no tissue available or no consent

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
improving folliculogenesis and oocuyte maturation after ovarian transplantation	2 years