NCT00827476Unknown早期 1 期
Phase 1 Study to Improve Results of Human Ovarian Transplantation
适应症
试验速览
- 阶段
- 早期 1 期
- 入组人数
- 100
- 主要终点
- improving folliculogenesis and oocuyte maturation after ovarian transplantation
研究概览
简要总结
we will perform xenotransplantation and in vitro culture of ovarian tissue from patients undergoing ovarian cortex cryopreservation.
详细描述
Ovarian tissue is removed by laparoscopy and only in patients facing premature ovarian failure due to chemotherapy.Tissue for research will consist either of a small portion (<10%) of the cortex for preservation for young women. another source of ovarian tissue for research will be obtained following consent from family of patients who have died of the disease and have previously frozen ovarian tissue.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 5 Years 至 40 Years（Child, Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •tissue previously obtained
排除标准
- •no tissue available or no consent
结局指标
主要结局
improving folliculogenesis and oocuyte maturation after ovarian transplantation
时间窗: 2 years
次要结局
未报告次要终点
研究者
相似试验
已完成
不适用
In Vitro Activation of Dormant Follicles for Patients With Primary Ovarian InsufficiencyNCT02322060The First Affiliated Hospital of Zhengzhou University35
招募中
不适用
Individualized Precision Treatment Based on Ovarian Cancer Organoid ModelOvarian CancerNCT05813509The First Affiliated Hospital of Xiamen University30
尚未招募
不适用
Ovarian tissue autotransplantation to improve quality of life for the young women with autoimmune disease or cancercancer or autoimmune diseaseJPRN-UMIN000045959Tohoku University Hospital5
已完成
不适用
Ovarian Rejuvenation for Premature Ovarian Insufficiency and Poor Ovarian ResponseInfertility, FemaleOvarian FailureNCT04163640Reproductive Medicine Associates of New Jersey90
已完成
3 期
A Prospective Study to Evaluate the Addition of Subcutaneous Recombinant Human-Luteinizing Hormone With Recombinant Human-Follicle Stimulating Hormone on Follicular Development in Women Undergoing Ovarian Stimulation for Assisted Reproductive TechnologiesOvarian StimulationInfertilityNCT01121991EMD Serono55