Influence of Inhaled Anaesthetics on Rebreathing of Carbon Dioxide When Using an Anaesthesia Gas Reflector (AnaConDa)

Not Applicable

Completed

• Conditions: Ischemic Heart Disease
• Interventions: Other: Inhaled anaesthetic agent

• Registration Number: NCT01699802
• Lead Sponsor: Region Skane

Brief Summary

The purpose is to investigate how the adsorptive capacity of the active carbon filter to carbon dioxide in an anaesthetic gas reflector (AnaConDa) is affected by adding inhaled anaesthetic agent.

The hypothesis is that addition of inhaled anaesthetic agent will affect the amount of adsorption of carbon dioxide to the active carbon and thereby affect rebreathing of carbon dioxide.

Detailed Description

Not available

Study Timeline

• Study Start: 2012-09
• Study First Submitted: 2012-09-25
• Study First Submitted QC: 2012-10-01
• Study First Posted: 2012-10-04
• Primary Completion: 2014-12
• Study Completion: 2014-12
• Status Verified: 2015-05
• Last Update Submitted: 2015-05-13
• Last Update Posted: 2015-05-14

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 12

Inclusion Criteria

• elective coronary artery by-pass graft surgery
• elective valve replacement surgery
• normal left ventricular ejection fraction on preoperative echocardiography

Exclusion Criteria

• obstructive lung disease
• restrictive lung disease

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Inhaled anaesthetic agent	Inhaled anaesthetic agent	The group where the investigators adds inhaled anaesthetic agent when using the anaesthetic gas reflector (AnaConda).

Primary Outcome Measures

Name	Time	Method
Volume of carbon dioxide rebreathing from an anesthetic gas reflector	2 hours	Tidal carbon dioxide volume rebreathed from an anesthetic gas reflector correlated to concentration of delivered anesthetic gas.

Secondary Outcome Measures

Name	Time	Method
Quantification of ventilatory requirements to maintain isocapnia with the use of an anesthetic gas reflector.	2 hours	Changes of tidal volume required to maintain constant alveolar ventilation will be assessed by continuous measurement of exhaled tidal carbon dioxide volume, the latter to be maintained at a constant value.

Trial Locations

Locations (1)

Skane University Hospital Lund, Cardiothoracic Intensive Care; 🇸🇪 Lund, Sweden