Use of Arimidex and Zoladex as Pretreatment to IVF in Women With Ovarian Endometriosis

Phase 4

Completed

• Conditions: Endometriosis

• Registration Number: NCT00286351
• Lead Sponsor: Rigshospitalet, Denmark

Brief Summary

Does a combination of Arimidex and Zoladex make endometriomas shrink and how is the following IVF outcome

Detailed Description

Not available

Study Timeline

• Study Start: 2005-01
• Study First Submitted: 2006-02-01
• Study First Submitted QC: 2006-02-01
• Study First Posted: 2006-02-03
• Status Verified: 2007-04
• Last Update Submitted: 2007-04-20
• Last Update Posted: 2007-04-23

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 20

Inclusion Criteria

• Endometrioma(s)with a size of 20-70 mm, persisted for at least 3 cycles
• Couples with indication and wish for IVF/ICSI
• Age of women: 20-40 years
• Regular menstrual cycle within normal range (21-35 days)
• Body Mass Index (BMI): 18-30 kg/m2

Exclusion Criteria

• History with osteoporosis, liver-, kidney- or heart disease or thromboembolic disease
• Treatment of endometriosis with GnRH agonist during the last 3 month

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
size of endometriomas after 2½ month of combined downregulation

Trial Locations

Locations (1)

The Fertility Clinic, Copenhagen University Hospital, Rigshospitalet; 🇩🇰 Copenhagen, Copenhagen East, Denmark