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临床试验/NCT01035372
NCT01035372已完成不适用

Pilot Study on the Tolerability of Dietary Dried Plum

University of California, San Francisco2 个研究点 分布在 1 个国家目标入组 6 人开始时间: 2009年12月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
6
试验地点
2
主要终点
urinary calcium excretion

研究概览

简要总结

Dried plums (Prunus domestica L.) have traditionally been recognized for their health benefits related to conditions such as constipation, irregular menstrual cycles and mouth sores. This dried fruit provides high levels of fiber, vitamins and minerals. Dried plum has also been shown in animal studies to have beneficial effects on bone and can prevent the loss of bone caused by low hormone levels such as occurs after surgical removal of the ovaries. We also have shown that dried plum can prevent the loss of bone associated with aging in mice. Very few therapies for osteoporosis actually reverse bone loss and improve bone strength. The potential therapeutic value of dried plum in men and women with hormone deficiency or age-related osteoporosis is clear.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Other
盲法
None

入排标准

年龄范围
50 Years 至 75 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Age between 50 yrs and 75 yrs
  • Nonsmokers
  • Normal renal and hepatic function

排除标准

  • Subjects who must follow a specific diet
  • Subjects on any daily medications that affect bone health
  • Subjects too heavy for the DEXA machine (weight limit 300 lbs)
  • Subjects whose BMD by DEXA indicates osteoporosis
  • Subjects unwilling to follow the diet specified
  • Pregnant women
  • Subjects who are unable to understand the consent form.

结局指标

主要结局

urinary calcium excretion

时间窗: one month

次要结局

  • ability to tolerate the diet(one month)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (2)

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