NL-OMON40725已完成4 期
Pharmacokinetic Profile of Ropivacaïne after Periarticular Local Infiltration Analgesia for Primary Total Knee Arthroplasty - LIAkin
适应症
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 20
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •- age 50-80 years
- •- ASA physical health classification I * II
- •- Body Mass Index (BMI) < 40
- •- patient planned for a primary unilateral posterior-stabilized tri-compartmental cemented total knee replacement (Genesis II - PS) under unilateral spinal anesthesia with 2 mL hyperbaric bupivacaine 0.5%
- •- scheduled for fast-track protocol TKA
- •- haemoglobin (Hb) concentration * 7.5 mMol/L
- •- written informed consent
排除标准
- •- Placement of a surgical drain
- •- Contra-indications for spinal anesthesia
- •- Known hypersensitivity to amide-type local anesthetics
- •- Hepatic or renal insufficiency
- •- Use of fluvoxamine, ciprofloxacin, ketoconazole, erythromycin, clarithromycin, itraconazole, or rifampicin because of their effect on ropivacaine clearance.
- •- Any other reason which in the opinion of the investigator makes the patient unsuitable for participation in the study
研究者
相似试验
进行中（未招募）
不适用
Study to descrive the processing of ropivacaine in the body when injected in the knee for pain treatment in total knee arthroplastypatients receiving primary total knee replacementEUCTR2014-003010-93-NLSint Maartenskliniek
进行中（未招募）
1 期
Study to describe the processing of ropivacaine in the body when injected in the knee for pain treatment in total knee arthroplastypatients receiving primary total knee replacementEUCTR2017-000180-32-NLSint Maartenskliniek Nijmegen20
已完成
不适用
Study to describe the processing of ropivacaine in the body when injected in the knee for pain treatment in total knee arthroplasty.Total Knee ArthroplastyRopivacainetourniquetPharmacokinetic profileTotale knieprotheseropivacainebloedleegtebandfarmacokinetisch profielNL-OMON24359Sint Maartenskliniek Nijmegen20
已完成
不适用
CLINICAL PHARMACOKINETICS OF ROPIVACAINE USING LOCAL INFILTRATION ANESTHESIA (LIA) TECHNIQUE IN THE TOTAL KNEE ARTHROPLASTY: A PILOT STUDYTotal knee arthroplasty (total knee replacement)10005944NL-OMON37901Reinier de Graaf Groep10
已完成
不适用
Population Pharmacokinetics of RopivacaineKnee OsteoarthritisNCT04702282Hvidovre University Hospital28