The effect of lidocaine on wakefulness during general anesthesia in elective cesarean sectio

Phase 3

Recruiting

Conditions: Effect of intravenous lidocaine on awareness during general anesthesia for elective cesarean section.
Other symptoms and signs involving cognitive functions and awareness
R41.8

Registration Number: IRCT20170314033069N7

Lead Sponsor: Rasht University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: Female

Target Recruitment: 52

Inclusion Criteria

Pregnant women candidates for caesarean section surgery under general anesthesia
American Society of Anesthesiologists (ASA) II, I
Hemodynamically stable condition

Exclusion Criteria

Inability to communicate appropriately verbally to fill out the questionnaire
sensitivity to local amide acetic acid
Any contraindications to the use of ondansetron (heart problems, especially Long Q-T)
Contraindications to Apotel (liver failure)
Contraindications to propofol (including drug-food allergies)
Contraindications to lidocaine, including heart blocks (bradydysrhythmias)
The presence of any psychiatric disorder that interferes with answering the questions.
A history of malignant hyperthermia that prohibits the use of inhaled gases and succinylcholine.

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The effectiveness of lidocaine on the frequency of different states of the first memory after regaining consciousness. Timepoint: 24 hours after surgery. Method of measurement: Face-to-face interview.;The effectiveness of lidocaine on the frequency of different states of the last memory before anesthesia of patients. Timepoint: 24 hours after surgery. Method of measurement: Face-to-face interview.;The effectiveness of lidocaine on the frequency of different conditions related to awareness during anesthesia. Timepoint: 24 hours after surgery. Method of measurement: Face-to-face interview.

Secondary Outcome Measures

Name	Time	Method
The effect of lidocaine on hemodynamic changes of patients (mean blood pressure and heart rate of the patient). Timepoint: 4 stations: base time (before injection of lidocaine), after intubation, end of operation, and after extubation. Method of measurement: Blood pressure and heart rate monitoring of patients.