Influence of donor's characteristics on the functional results of penetrating and lamellar keratoplasties

Recruiting

• Conditions: H18.1; H18.5; Hereditary corneal dystrophies; Bullous keratopathy

• Registration Number: DRKS00017451
• Lead Sponsor: niversitätsmedizin der Johannes Gutenberg-Universität Mainz

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2019-06-21
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 202

Inclusion Criteria

DMEK group: male or female; > 18 years of age; phakic or pseudophakic; diagnosis of Fuchs endothelial dystrophy or corneal endothelial failure - indication for DMEK
PKP group: male or female; > 18 years of age; phakic or pseudophakic; diagnosis of corneal diseases or scars - indication for penetrating keratoplasty

Exclusion Criteria

History of penetrating or lamellar keratoplasty; indication for HLA-typed keratoplasty; patient not able to participate in the study

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Best corrected visual acuity 12 months after keratoplasty

Secondary Outcome Measures

Name	Time	Method
Endothelial cell count 12 months after keratoplasty