Thoracic Fluid Content and Acute Lung Injury

Completed

• Conditions: Acute Lung Injury
• Interventions: Device: NICOM

• Registration Number: NCT01922557
• Lead Sponsor: National Taiwan University Hospital

Brief Summary

To study the association of the thoracic fluid content and acute lung injury during liver transplantation.

Detailed Description

Acute lung injury is not uncommon after liver transplantation. A new monitor non-invasive cardiac output monitor (NICOM) is designed to measure thoracic fluid content. The investigators attempt to use the parameter thoracic fluid content to investigate its relationship with acute lung injury in liver transplant recipients.

Study Timeline

• Study Start: 2011-01
• Primary Completion: 2011-01
• Study Completion: 2012-06
• Study First Submitted: 2013-07-11
• Status Verified: 2013-08
• Study First Submitted QC: 2013-08-12
• Last Update Submitted: 2013-08-12
• Study First Posted: 2013-08-14
• Last Update Posted: 2013-08-14

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 22

Inclusion Criteria

• end stage liver disease scheduled for liver transplantation in National Taiwna University Hospital.

Read More

Exclusion Criteria

• allergic reaction
• history of aortic regurgitation
• pre-existing pulmonary disease

Read More

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
NICOM	NICOM	-

Primary Outcome Measures

Name	Time	Method
Cardiac index	one day	Participants will be followed for the duration the operation. Cardiac index was measured by non-invasive cardiac output monitor at different time points as baseline(T1), anhepatic phase(T2), 30 mins after reperfusion(T3) and 2 hrs after reperfusion(T4)

Secondary Outcome Measures

Name	Time	Method
Thoracic fluid content	one day	Participants will be followed for the duration the operation.Thoracic fluid content was measured in liver transplant recipients at different time points as baseline(T1), anhepatic phase(T2), 30 mins after reperfusion(T3) and 2 hrs after reperfusion(T4).

Trial Locations

Locations (1)

Department of Anesthesiology, NTUH; 🇨🇳 Taipei, Taiwan