Influence of Muscle Relaxation With Rocuronium Bromide During General Anaesthesia on Muscle Trauma and Postoperative Analgetic Consumption in Patients With Total Hip Prosthesis Implantation
Phase 4
Completed
- Conditions
- Muscle RelaxationMuscle TraumaAnalgetic ConsumptionTotal Hip Replacement
- Registration Number
- NCT01228162
- Lead Sponsor
- Klinikum Hildesheim GmbH
- Brief Summary
The researchers want to investigate the effects of muscle relaxation with rocuronium bromide during general anaesthesia on muscle trauma (serum CK, CRP) and postoperative analgesic consumption in patients with total hip prosthesis replacement (general vs. spinal anaesthesia).
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 120
Inclusion Criteria
- patient agreement
- indication for total hip replacement
- age 55 - 80 years
- weight 65 - 95 kg
- first intervention
- ASA classification I - III
- general and spinal anaesthesia possible in this patient
Exclusion Criteria
a) neuromuscular diseases b) surgery with muscle trauma (within the last 3 months) c) permanent immobility d) intramuscular injections (within the last 4 weeks) e) medication with opioids f) medication with co-analgetics g) contraindications for general or spinal anaesthesia h) dementia, cognitive dysfunction or sleep apnea
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method degree of muscle trauma 24 hours serum CK and CRP levels are measured
- Secondary Outcome Measures
Name Time Method consumption of analgetics 3 days consumption of piritramide is measured
Trial Locations
- Locations (1)
Klinikum Hildesheim GmbH
🇩🇪Hildesheim, Germany
Klinikum Hildesheim GmbH🇩🇪Hildesheim, Germany