Ex-vivo/in vitro studies on immune-activators and blockers in hidradenitis suppurativa

Withdrawn

• Conditions: De proefpersonen fungeren als de controle groep van patienten met de huidziekte hidradenitis suppurativa.; acne inversa; verneuil's disease

• Registration Number: NL-OMON50846
• Lead Sponsor: Erasmus MC, Universitair Medisch Centrum Rotterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 9 April 2024

Recruitment & Eligibility

• Status: Withdrawn
• Sex: Not specified
• Target Recruitment: 30

Inclusion Criteria

Inclusion criteria cases - hidradenitis suppurativa patients
- Participating in HiScreen Biobank
- Informed consent available for bloodsamples

Inclusion healthy volunteers
- Adult (>18 years old) not suffering from HS
- Competent and willing to provide informed consent

Exclusion Criteria

Exclusion criteria for hidradentis suppurativa patients
- <18 years of age
- use of systemic or local antibiotics in the past 2 weeks
- use of any other medication potentially affecting the cytokine/antimicrobial
profiles
- pregnant women
Exclusion criteria controls
- <18 years of age
- known with hidradenitis suppurativa
- use of any other medication potentially affecting the cytokine/antimicrobial
profiles
- pregnant women
- relatives with hidradenitis suppurativa

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The main study parameter is the difference of immune response to above<br /><br>mentioned hidradenitis suppurativa triggering factors, forexample the<br /><br>cytokine/antimicrobial profile after microbial exposure in HS patients compared<br /><br>to healthy controls.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>N.A.</p><br>