Is the Use of Fibrinogen in Cesarean Section Related to Bleeding and Blood Product in Patients With Placenta Accreta Spectrum?: a Retrospective Randomized Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 146
- 试验地点
- 1
- 主要终点
- Laboratory hemoglobin level(g/dl)
研究概览
简要总结
The aim of this study is to evaluate the relationship between fibrinogen use and bleeding in patients who underwent cesarean section with a prediagnosis of PAS.
The key question(s) it aims to answer are:
[Does the use of fibrinogen concentrate reduce bleeding in PAS patients?] Patients who had a cesarean section with a pre-diagnosis of PAS were analyzed retrospectively. The choice of anesthesia applied to the patients and the relationship between the use of blood products and bleeding were evaluated.
详细描述
Our study was designed as a retrospective randomized study. Patients aged 20-50 years and >34 weeks of gestation who accepted the birth with a cesarean section with a pre-diagnosis of PAS were evaluated retrospectively.
examined. were randomized into 2 groups, 53 patients in each group: group1: GNF : the group without fibrinogen concentrate
Group 2: GF: the group with fibrinogen concentrate
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
盲法说明
retrospective randomized study
入排标准
- 年龄范围
- 20 Years 至 50 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •20-50 years PAS pre-diagnosed pregnant women
- •>34 weeks of pregnancy
- •Those with normal renal functions
排除标准
- •Patients with renal insufficiency
- •Those with <34 weeks of gestation
- •Pregnant women with missing data
结局指标
主要结局
Laboratory hemoglobin level(g/dl)
时间窗: Change from preoperative to postoperative day 1(POD 1) hemoglobin values (g/dl).
Our primary aim was to evaluate the postoperative day 1(POD 1) hemoglobin values(g/dl).
次要结局
- The intensive care unit (ICU) admission and length of stay.(postoperatively up to 1 months)
研究者
Duygu Akyol
Principal Investigator
Bakirkoy Dr. Sadi Konuk Research and Training Hospital