Treatment of Obstetric Hemorrhage With Fibrinogen and Blood Products: Retrospective Analyzes
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 56
- 试验地点
- 1
- 主要终点
- Measurement of fibrinogen (mg/L)
研究概览
简要总结
The files of hemorrhagic obstetric patients undergoing surgery and followed in the intensive care unit and using Fibrinogen and blood products were included in the study between January 2015- September 2018 at the Anesthesiology and Reanimation Clinic of SBU Kanuni Sultan Süleyman Training and Research Hospital. Patients under 18 years of age were excluded from the study. In this study, ages, operation types, number of blood and products, the amount of fibrinogen, the results of the hemogram and bleeding parameters, the levels of fibrinogen, the duration of hospital stay and the intensive care unit were recorded.
详细描述
Bleeding is an important event that threatens the patient's life. Too much blood and blood products can be used in massive bleeding. However, unwanted allergic reactions may occur in blood and blood product transfusions. Fibrinogen is the first coagulation factor in coagulopathy. Some studies have shown that when the fibrinogen level falls to <150-200 mg / dl, the bleeding increases dramatically.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Obstetric patients, underwent surgery and followed in ICU
- •Used Fibrinogen and Blood products
- •Over 18 years age
排除标准
- •Under 18 years age
- •Obstetric patients, underwent surgery but not used Fibrinogen and Blood products
结局指标
主要结局
Measurement of fibrinogen (mg/L)
时间窗: 24 hours
Significant independent predictor for evolution to severe PPH was plasma fibrinogen level.
Amount of blood products (unit)
时间窗: 24 hours
degree of hemorrhagie
Measurement of hemoglobin (g/dL)
时间窗: 24 hours
Postpartum hemorrhage (PPH) is a major contributor to maternal death and severe maternal morbidity
Amount of fibrinogen consantrates
时间窗: 24 hours
in order to avoid PPH
次要结局
- Hospital stay days(24 hours)
研究者
Ayca Sultan Sahin
Principal Investigator
Kanuni Sultan Suleyman Training and Research Hospital