A Multi-center Study on Effect of Cemented Implantation in Shoulder Replacement on Blood Pressure
试验速览
- 阶段
- 不适用
- 入组人数
- 350
- 主要终点
- Change from Baseline Systolic Blood Pressure
研究概览
简要总结
To clarify the downward trend of blood pressure affected by bone cement implantation during shoulder replacement operations.
详细描述
A total of 350 cases of proximal humeral fracture are planned to be recruited and receive semi-shoulder replacement in Department of Orthopedics and Trauma，Peking University People's Hospital．The blood pressure data are collected from patients' anesthesia records. Both the systolic and diastolic blood pressure are recorded at four time spots during operation: the time before using of bone cement (time period A), 0-5 min after using cement (time period B), 5-10 min after using cement (time period C) and 10-15min after using cement (time period D). The data of blood pressure are collected according to anesthesia records．
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients with three or four part of proximal humeral fracture receiving cemented shoulder replacement
排除标准
- •pathologic fracture
- •severe hypertension or hypotension
结局指标
主要结局
Change from Baseline Systolic Blood Pressure
时间窗: Change from Baseline Systolic Blood Pressure at 15 mins
the systolic blood pressure after insert the cemented stem
次要结局
- Change from Baseline Diastolic Blood Pressure(Change from Baseline Diastolic Blood Pressure at 15 mins)
研究者
Zhang Peixun
Clinical Professor
Peking University People's Hospital