Efficacy of Social Cognition Training in Schizophrenia

Not Applicable

Active, not recruiting

• Conditions: Schizophrenia
• Interventions: Behavioral: Social Cognition Interaction Training; Behavioral: WLC

• Registration Number: NCT00587561
• Lead Sponsor: VA Connecticut Healthcare System

Brief Summary

The term social cognition refers to how social information is processed. Individuals with schizophrenia and schizoaffective disorder have been shown to have significant deficits in social cognition. Moreover, it has been speculated that these deficits may in turn have a negative impact on their overall functioning. Behavioral interventions targeting social cognition are just beginning to emerge, and there is a need to evaluate their efficacy.

Objectives:

This is a small trial evaluating the efficacy of social cognition interaction training (SCIT) an experimental behavioral treatment for improving social cognition in schizophrenia.

Research Design and Methodology:

Approximately 48 participants with schizophrenia-spectrum disorders will be randomized into one of two conditions: 1) a 20 to 24 session manualized social cognition interaction training group (SCIT), or 2) wait-list control. Pre-and post-group therapy assessments of symptoms, social cognition, basic cognition, and community function will be conducted. Data obtained from this study will allow us to determine the efficacy of SCIT training in improving symptom, cognitive, and functional measures.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2007-12-21
• Study First Submitted QC: 2007-12-21
• Study Start: 2008-01
• Study First Posted: 2008-01-07
• Primary Completion: 2013-12
• Status Verified: 2023-04
• Last Update Submitted: 2023-04-28
• Last Update Posted: 2023-05-01
• Study Completion: 2023-12

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: All
• Target Recruitment: 75

Inclusion Criteria

• diagnosis of schizophrenia or schizoaffective disorder
• Age between 18 and 65
• minimum of 30 days since discharge from last hospitalization
• minimum of 30 days since last change in psychiatric medications
• no housing changes in the past 30 days

Exclusion Criteria

• current diagnosis of alcohol or substance abuse/dependence
• history of brain trauma or neurological disease
• mental retardation or developmental disability
• auditory or visual impairment that would interfere with study procedures

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
1 Social Cognition Interaction Training	Social Cognition Interaction Training	Will receive 20-26 sessions of a manualized group treatment called Social Cognition Interaction Training
2 Wait List Control	WLC	Wait list control; 6 months of treatment as usual followed by Social Cognition Interaction Training group

Primary Outcome Measures

Name	Time	Method
Social cognitive measures	intake, 6 months

Secondary Outcome Measures

Name	Time	Method
basic cognitive measures	intake, 6 months

Trial Locations

Locations (2)

VA Connecticut Healthcare System; 🇺🇸 West Haven, Connecticut, United States

Connecticut Mental Health Center; 🇺🇸 New Haven, Connecticut, United States