Social Cognition and Social Functioning in Schizophrenia
Completed
- Conditions
- Schizophrenia10039628
- Registration Number
- NL-OMON44578
- Lead Sponsor
- Psychiatrie
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 120
Inclusion Criteria
Aged 18-50
Give written informed consent
Dutch speaking
Premorbid IQ>80
Patients: DSM-IV diagnosis in the schizophrenia spectrum
Exclusion Criteria
Drug or alcohol abuse over a period of six months prior to the experiment
History of closed-head injury
History of neurological illness or endocrinological dysfunction
Chronical use of medication (patients: medication other than psychiatric medication)
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>- Relation between classic social cognition, self-other distinction processes,<br /><br>and social functioning in patients with schizophrenia, compared with matched<br /><br>healthy controls.<br /><br>- Relation between brain morphology (volume, cortical thickness, white matter<br /><br>tracts) and social functioning and social cognition.<br /><br>- Relation between fMRI activation in medial prefrontal cortex, amygdala<br /><br>cingulate cortex and emotion processing and self referential task<br /><br>- Relation between activation during self-referential or emotion processing<br /><br>and self-other distinction and social functioning </p><br>
- Secondary Outcome Measures
Name Time Method <p>n.a.</p><br>