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The efficacy and safety of Zhuangyao Tongluo Decoction in the treatment of lumbar disc herniation:a randomized,double- blind,double-simulated,parallel control clinical study

Phase 1
Conditions
umbar disc herniation
Registration Number
ITMCTR2022000034
Lead Sponsor
China Academy of Chinese Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
All
Target Recruitment
Not specified
Inclusion Criteria

1)Comply with the diagnostic criteria of lumbar disc herniation;
2) Aged between 18 and 75 years old;
3)If you have received other conservative treatment, you need more than 7 days of wash-out period;
4) Volunteer to participate, sign the informed consent form, and be willing to accept the test;
5)leg VAS pain score = 4 and < 7.
Those who meet the above five options are eligible for this clinical study.

Exclusion Criteria

1 ) Patients with spinal infections, tumors, tuberculosis, traumatic fractures, ankylosing spondylitis, etc.
2 ) Patients with severe pain, cauda equina nerve symptoms or lower limb muscle strength decrease who met the surgical indications.
3 ) Patients with previous lumbar surgery ;
4 ) Pregnancy and lactation women.
5 ) Patients with mental diseases or other reasons that do not cooperate.
6 ) Patients with severe cardiovascular, renal, liver, gastrointestinal ulcers, hematopoietic system diseases.
7 ) Patients with allergic constitution or known allergy to drugs and their components ( including sulfonamides ) used in this experiment.

Study & Design

Study Type
Interventional study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
VAS scores of leg pain;
Secondary Outcome Measures
NameTimeMethod
SF-12;ODI scores;JOA scores;VAS scores of lumbar pain;
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