Effects of yoga and meditation on motor function, objective and subjective sleep in Parkinsons disease: a pilot randomized controlled trial
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 30
- 试验地点
- 1
研究概览
简要总结
This pilot randomized controlled trial investigates the feasibility, acceptability, and preliminary effects of yoga and meditation on motor function and sleep outcomes in Parkinson disease patients. Parkinson disease a progressive neurodegenerative disorder often leads to sleep dysfunction with reduced efficiency while pharmacologic treatments cause side effects and limited non-pharmacologic options exist. This study addresses this gap by randomly allocating 30 patients (10 per group: yoga, meditation, control) with idiopathic PD (Hoehn-Yahr stage 1-3, age greater than equal to 45, stable medications) excluding comorbidities or prior yoga meditation practitioners.
Over 12 weeks, yoga and meditation groups receive twice-weekly 50-minute supervised sessions alongside routine care; yoga includes poses like mountain, warrior, and cobra; meditation features mindful breathing and mantras. The control group undergoes standard rehabilitation program. Outcomes are assessed at baseline and post-intervention: primary measures include motor function via Unified PD Rating Scale (UPDRS) motor score, objective sleep (actigraphy efficiency, total sleep time, latency, wake after sleep onset), and subjective sleep (PDSS). Secondary objectives evaluate feasibility and group comparisons.
Analysis uses paired t tests for within group changes, linear regression for between-group effects (controlling confounders like gender BMI, modifier medication), and descriptive statistics in SPSS. With a convenience sample of 30, this pilot draws from similar studies, prioritizing ethical consent and bias mitigation via validated tools. Expected outcomes include improved sleep motor function, informing targeted interventions with minimal risks (mild yoga discomfort) and societal benefits for elderly PD management.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Outcome Assessor Blinded
入排标准
- 年龄范围
- 45.00 Year(s) 至 70.00 Year(s)(—)
- 性别
- All
入选标准
- •Idiopathic PD Hoehn and Yahr stage 1-3 stable medication regimen for at least four weeks prior to study entry.
排除标准
- •atypical or secondary Parkinsonism multiple strokes inability to walk without a walker Montreal Cognitive Assessment (MoCA) score less than or equal to 26 deep brain stimulation untreated sleep apnea, coronary artery disease, Diabetes mellitus, chronic obstructive pulmonary disease, chronic kidney disease, had a decline in immune function such as pneumonia or systemic infection patients who were already practicing yoga and meditation regularly.
研究者
Dr MEENA MIRDHA
AIIMS Bathinda
