Influence of Warfarin on Thromboelastography and Transfusion
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 107
- 试验地点
- 1
- 主要终点
- Rotational Thromboelastography : Clotting time (CT)
研究概览
简要总结
Warfarin therapy is usually monitored using the international normalized ratio (INR), and prolonged INR means coagulation impairment that can leads elevating transfusion requirement after operation. This study was designed to assess the relationships with warfarin and TEG values related to transfusion amount, to set up blood transfusion strategy in patients on atrial fibrillation undergoing cardiac surgery.
详细描述
This study was a retrospective evaluation of patients who have received cardiac surgery with Maze-operation from March 2008 to November 2013.
Patients who have atrial fibrillation undergoing cardiac surgery with Maze-operation were included.
The following exclusion criteria are applied:
- Patients who have taken medicine related to coagulation (such as antiplatelets like aspirin and clopidogrel) except warfarin or bridged heparin
- Patients whose laboratory values could not be confirmed by medical records review.
Patients were categorized by two groups.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 20 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients who have atrial fibrillation undergoing cardiac surgery with Maze-operation.
- •W group : Patients who have had warfarin therapy before operation due to treat Atrial fibrillation
- •C group : Patients who have not had warfarin therapy before operation
排除标准
- •Patients who have taken medicine related to coagulation (such as antiplatelets like aspirin and clopidogrel) except warfarin or bridged heparin.
- •Patients whose laboratory values could not be confirmed by medical records review.
结局指标
主要结局
Rotational Thromboelastography : Clotting time (CT)
时间窗: 30min after anesthetic induction and 15 mins after CPB weaning status
次要结局
- Rotational Thromboelastography : clot formation time (CFT)(30min after anesthetic induction and 15 mins after CPB weaning status)