NCT01183962终止不适用
Vitamin D and T-Regulatory Cells in Coronary Artery Disease
适应症
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 入组人数
- 50
- 试验地点
- 2
- 主要终点
- increase in T-regulatory Cells
研究概览
简要总结
The purpose of this study is to evaluate the effect of Vitamin D supplementation on cardiovascular disease and certain cells (T-regulatory cells) in the body that play a role in plaque formation in arteries. This study will determine the levels of Vitamin D and T-regulatory cells in subjects with coronary artery disease and if Vitamin D supplementation will affect future events such as heart attach and stroke.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 30 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •between the ages of 30 and 80 years
- •have a history of medically treated coronary artery disease
排除标准
- •history of smoking in the past 2 years
- •history of diabetes mellitus
结局指标
主要结局
increase in T-regulatory Cells
时间窗: 1 year
We expect significant improvement in the suppressive capacity, with or without increase in the number, of circulating T-regs after vitamin D supplementation. This increase in T-regs function will correlate with improvement in clinical parameters.
次要结局
- decrease pro-inflammatory cytokines & sTNFR1 and increase serum IL-10(1 year)
研究者
研究点 (2)
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