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Comparative efficacy of Cyproheptadine and Baclofen on spasticity in patients with head trauma

Phase 2
Conditions
Head Trauma.
Multiple superficial injuries of head
Registration Number
IRCT2014041112777N1
Lead Sponsor
Vice chancellor for research, Ahvaz Jundishapur University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
40
Inclusion Criteria

Patients with diffuse axonal injury without chronic hepatic or renal disease; 15 to 60 years old.
Exclusion criteria: Changing in treatment plan like surgery; drug reactions; drug side effects.

Exclusion Criteria

Not provided

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Spasticity. Timepoint: 1, 3, 6, 9, 12, 15 days. Method of measurement: Modified Ashworth Scale.
Secondary Outcome Measures
NameTimeMethod
Alanine Transaminase (ALT). Timepoint: Weekly. Method of measurement: U/ml.;Blood Urea Nitrogen(BUN). Timepoint: Daily. Method of measurement: Mg/dl.;Aspartate Amino Transferase(AST). Timepoint: Weekly. Method of measurement: U/ml.;Alkaline Phosphatase(ALP). Timepoint: Weekly. Method of measurement: U/ml.;Creatinine. Timepoint: Daily. Method of measurement: Mg/dl.
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