Study of tolerability, biodistribution and dosimetry of Technetium-99m radiolabelled Fucoida

Completed

• Conditions: Fucoidan; P-selectin; cardiovascular disease; atherosclerosis; thrombosis

• Registration Number: NL-OMON24363
• Lead Sponsor: Academic Medical Center Amsterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 28 February 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 10

Inclusion Criteria

In order to be eligible to participate in this study, a subject must meet all of the following criteria:

-Adult subjects of either gender, aged 18 years or older

Exclusion Criteria

A potential subject who meets any of the following criteria will be excluded from participation in this study:

-Progressive and chronic disease

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Tolerability will be evaluated on the frequency and severity of adverse events, as well as on the following parameters: <br /><br>-Vital signs<br /><br>-Physical examination<br /><br>-ECG <br /><br>-Clinical blood laboratory measurements<br>

Secondary Outcome Measures

Name	Time	Method
-Biodistribution (blood clearance and tissue biodistribution)<br /><br>-Dosimetry (effective dose in mSv per organ and per individual determined from biodistribution)<br>