Efficacy of Buprenorphine on Postoperative Endodontic Analgesia
试验速览
- 阶段
- 1 期
- 状态
- 终止
- 入组人数
- 10
- 试验地点
- 1
- 主要终点
- The Efficacy of Buprenorphine in addition to Local Anesthetic in Providing Prolonged Postoperative Endodontic Analgesia
研究概览
简要总结
To see whether the addition of buprenorphone to local anesthesia will lengthen postoperative analgesia for endodontic pain
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •persons with preoperative pain to percussion of a tooth with pulpal disease requiring endodontic therapy, healthy individuals, ASA Class I and II, no known allergies to the drugs being administered
排除标准
- •pregnancy, allergy to buprenorphine, allergy to local anesthetic
研究组 & 干预措施
buprenorphine and local anesthetic
buprenorphine added to local anesthetic
干预措施: Buprenorphine (Drug)
buprenorphine and local anesthetic
buprenorphine added to local anesthetic
干预措施: lidocaine, epinephrine (Local anesthetic) (Drug)
sterile saline and local anesthetic
sterile saline (placebo) added to local anesthetic
干预措施: Sterile saline (Drug)
sterile saline and local anesthetic
sterile saline (placebo) added to local anesthetic
干预措施: lidocaine, epinephrine (Local anesthetic) (Drug)
结局指标
主要结局
The Efficacy of Buprenorphine in addition to Local Anesthetic in Providing Prolonged Postoperative Endodontic Analgesia
时间窗: two years
The number of patients with extended postoperative analgesia when compared to the baseline in pain scores on a visual analog scale during a three-day period will be analyzed. A questionnaire containing a visual analog scale and a log for recording the use of rescue analgesics will be used to gather the data.
次要结局
未报告次要终点
研究者
Thomas A. Montagnese
Associate Professor
University Hospitals Cleveland Medical Center