Do Childhood Measles and DTaP Vaccination Decrease the Mortality Rate Caused by COVID-19 in OECD Countries?

Completed

• Conditions: Covid19; Measles Vaccine; Mortality

• Registration Number: NCT04468802
• Lead Sponsor: Kanuni Sultan Suleyman Training and Research Hospital

Brief Summary

Mortality rates caused by SARS CoV-2 differ between countries and this difference might be explained by several reasons. Childhood vaccination rate is thought to be one of them. Therefore present study aimed to examine the possible relationship between DTaP (diphtheria, tetanus, pertussis) and measles vaccination rates of Organization for Economic Co-operation and Development (OECD) countries and case fatality rate (CFR) caused by SARS CoV-2.

Detailed Description

The mortality rates caused by SARS CoV-2 differ between countries and this difference might be explained by several reasons. Childhood vaccination rate is thought to be one of them. Therefore present study aimed to examine the possible relationship between DTaP (diphtheria, tetanus, pertussis) and measles vaccination rates of Organization for Economic Co-operation and Development (OECD) countries and case fatality rate (CFR) caused by SARS CoV-2.A total of 32 OECD countries, of northern hemisphere, have been included in this study. Statistical analysis performed according to the CFR data of these countries based on SARS CoV-2. The CFR data calculated according to the total mortality count of a specific country for the 3-month period down from the date when first SARS CoV-2 case was observed.

Study Timeline

• Study Start: 2020-02-01
• Primary Completion: 2020-06-30
• Status Verified: 2020-07
• Study Completion: 2020-07-01
• Study First Submitted: 2020-07-09
• Study First Submitted QC: 2020-07-09
• Last Update Submitted: 2020-07-10
• Study First Posted: 2020-07-13
• Last Update Posted: 2020-07-14

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 32

Inclusion Criteria

• Children vaccinated in OECD countries in northern hemisphere

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Exclusion Criteria

• Non vaccinated children
• Southern hemisphere countries
• non-OECD countries

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Case Fatality Rate	4 months	Mortality rate caused by SARS CoV-2

Trial Locations

Locations (1)

Istanbul Kanuni Sultan Suleyman Training and Research Hospital; 🇹🇷 Istanbul, Kucukcekmece, Turkey