Sunlight exposure and vitamin D in the ageing populatio

Not Applicable

Completed

• Conditions: Specialty: Dermatology, Primary sub-specialty: Dermatology; UKCRC code/ Disease: Musculoskeletal/ Disorders of bone density and structure; Skin and Connective Tissue Diseases; Dermatology

• Registration Number: ISRCTN14201277
• Lead Sponsor: niversity of Manchester

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2016-11-16
• Study Completion: 2019-05-31
• Last Update Posted: 25 January 2021

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 125

Inclusion Criteria

1. Healthy, ambulant, male and female adults aged 65-84 years
2. White Caucasian
3. Willing and capable of participating to the extent and degree required by the protocol

Exclusion Criteria

1. Taking medication influencing vitamin D, or that is bone-active or photoactive
2. History of sunbathing/sunbed use within 3 months
3. History of skin cancer or photosensitivity
4. Taking any vitamin D, fish oil or calcium supplements (intervention study only)

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Serum 25-hydroxyvitamin D concentration measured by liquid chromatography/tandem mass-spectrometry at baseline, 1, 2, 3, 4, 5 and 6 weeks (intervention study) and in September and January (observation study).

Secondary Outcome Measures

Name	Time	Method
<br> 1. Serum parathyroid hormone measured at baseline and week 6 (intervention) and in September and January (observation)<br> 2. Bone turnover markers measured at baseline and week 6 (intervention) and in September and January (observation)<br> 3. Dietary vitamin D intake assessed thorough diet logs at baseline and week 6 (intervention) and in September and January (observation)<br> 4. Sun exposure measured by dosimeter badges and diaries in September and January (observation only)<br>