Recovery of walking after Knee Replacement with ROCC
- Conditions
- knee arthrosisknee osteoarthritis10023213
- Registration Number
- NL-OMON31531
- Lead Sponsor
- Vrije Universiteit Medisch Centrum
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 20
age between 40 and 80, unilateral osteoarthritis of the knee, waitlisted for knee replacement with the ROCC at the Gemini Hospital in Den Helder or the Albert Schweizer Hospital in Zwijndrecht
replacement of the other knee (earlier, scheduled, or to be scheduled), revision operation, any conditions than osteoarthritis of the knee that interfere with gait (such as neurological, skeletomuscular, or obstetric disorders), any conditions that render the patient unfit to be tested (such as pulmonary and/or cardiac disorders), any conditions that render the patient unable to understand or adhere to the protocol (such as cognitive, visual and/or language problems, or hand problems, that render the patient unfit to fill-in the questionnaires)
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Gait parameters and directly related measurements:<br /><br>- maximum walking velocity<br /><br>- comfortable walking velocity<br /><br>- gait kinematics<br /><br>- the DynaPort KneeTest for activities of daily living (ADL).</p><br>
- Secondary Outcome Measures
Name Time Method <p>[Independent: Demographic data, such as age, gender, weight, medical intake<br /><br>(co-morbidity, co-interventions).]<br /><br><br /><br>Knee Society Knee Score<br /><br><br /><br>Scores on<br /><br>questionnaires:<br /><br><br /><br>- the SF36 for health-related quality of life.<br /><br>- the WOMAC for osteoarthritis-related quality of life<br /><br>- the TAMPA scale for fear of movement<br /><br>- the IPAQ for the amount of physical activity<br /><br>- a question about the priority given to daily routines<br /><br>- VAS-scores before and after the experiment, as to expected / experienced<br /><br>pain, fatigue, anxiety<br /><br><br /><br>Quadriceps strength<br /><br>Oxygen consumption during walking<br /><br>Serum concentrations of inflammation mediators, such as IL6 and CRP.</p><br>