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临床试验/NCT05917418
NCT05917418尚未招募不适用

Impact of Nutritional Support on Outcome,Cost/Effectiveness for Patient at Risk

Peking Union Medical College4 个研究点 分布在 1 个国家目标入组 400 人开始时间: 2026年12月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
400
试验地点
4
主要终点
The incidence of Infectious complication

研究概览

简要总结

The impact of nutritional support for the patients at nutritional risk on clinical outcomes and cost-effectiveness.

详细描述

Although it was often to hear that malnutrition ratio in Aisa hospitalized patient was 40%-70% , there was no evidence to elaborate the prevalence of nutritional risk and malnutrition on hospitalized patients of Asia. Also in USA no data for nutritional risk. In 2002, scientists group headed by Kondrup from : European Society for Parenteral and Enteral Nutrition demonstrated that randomized controlled clinical trials showed patients may get benefit from nutrition support when they with nutrition risk. Based on these evidences, a simpler method was established by European Society for Parenteral and Enteral Nutrition in year 2002 in Munich & it was demonstrated useful to evaluate the appropriate use of nutrition support at present time. This method was named as Nutrition Risk Screening (NRS).

Investigators propose to survey the prevalence of malnutrition & nutrition risk in large cities' large/middle size hospitalized patients in China, Europe and USA use NRS tool. As well, we also aim to figure out the current nutrition support status in current large/middle size hospitals through this survey.

Investigators also propose to evaluate the cost-effectiveness of parenteral nutrition, enteral nutrition and non-nutritional support, and to examine the clinical outcomes of nutritional support in certain patients at nutritional risk identified by NRS-2002.

For international cooperation, the partners are Professor Kondrup of Europe and Professor Nolan from Johns Hopkins Hospital,there are students from a cooperative project with Johns Hopkins Hospital for Doctor of Philosophy students 2005-2011.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Supportive Care
盲法
Single (Outcomes Assessor)

入排标准

年龄范围
18 Years 至 90 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • patients be in hospital overnight
  • diagnoses according to the protocol of cohort study for cost effectiveness

排除标准

  • patients admitting from emergency department
  • patients who undergone operation before second morning of hospitalization
  • patients who dose not give Informed Consents

研究组 & 干预措施

Nutritional support therapy group

Experimental

All participants in this group will receive proper nutritional support.

干预措施: nutritional support (Dietary Supplement)

Routine hospital management group

No Intervention

All participants in this group will receive routine hospital management, without additional nutritional interventions.

结局指标

主要结局

The incidence of Infectious complication

时间窗: during the hospital stay

A infectious complication was defined as as the presence of recognized pathogens in body tissues that normally are sterile, confirmed by the results of culture and supported by clinical, radiologic or hematologic evidence of infection

次要结局

  • Total cost amount(during the hospital stay)

研究者

发起方
Peking Union Medical College
申办方类型
Other
责任方
Principal Investigator
主要研究者

Zhu-ming Jiang

Professor of General Surgery

Peking Union Medical College

研究点 (4)

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