Transmission of SARS-CoV-2 within Dutch households
Completed
- Conditions
- COVID-19, SARS-CoV-2
- Registration Number
- NL-OMON29654
- Lead Sponsor
- ational Institute for Public Health and the Environment (RIVM)
- Brief Summary
https://pubmed.ncbi.nlm.nih.gov/33822007/
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 250
Inclusion Criteria
Any person 16 years and older testing positive for SARS-CoV-2 (index case) who had at least one child in their household below the age of 18 and consented to be contacted for scientific research. Every household contact (persons living in the same house as the index patient) was to be enrolled in the study.
Exclusion Criteria
Household contacts below the age of 1. Households were excluded if one or more of the household contacts did not want to participate in the study upfront.
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To estimate secondary attack rates of SARS-CoV-2 and determine factors that impact susceptibility and infectiousness.
- Secondary Outcome Measures
Name Time Method To determine the clinical presentation of COVID-19. <br>To determine the proportion of symptomatic and asymptomatic SARS-CoV-2 infections within households. <br>To determine the dynamics and the anatomical sites of virus replication in COVID-19 cases. <br>To determine immunological dynamics in COVID-19 cases. <br>To assess the serological and cellular immune response of COVID-19 cases.