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A comparative study of effect of intravenous labetalol, esmolol and lignocaine in attenuation of sympathomimetic changes to laryngoscopy and endotracheal intubatio

Phase 1
Conditions
Health Condition 1: O- Medical and Surgical
Registration Number
CTRI/2023/07/055301
Lead Sponsor
DrRADHA
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

Patients of ASA I and ASA II category undergoing general anaesthesia with endotracheal intubation.

Exclusion Criteria

Patients of ASA grade III or more.

Ischemic heart disease.

Hypertension.

Anticipated difficult airway.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
To compare haemodynamic changes across all 3 groups <br/ ><br>during & immediately after laryngoscopy & endotracheal intubation.Timepoint: 2 years
Secondary Outcome Measures
NameTimeMethod
To compare the clinically significant adverse effects like bradycardia, hypotension requiring treatment. Definitions : Heart rate less than 50bpm is defined as bradycardia requiring treatment. Hypotension requiring treatment is defined as MAP less than 60 mmHgTimepoint: 2 YEARS
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