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Effects of Marijuana Used on Lung Function in Persons With Chronic Obstructive Pulmonary Disease (COPD)

Completed
Conditions
Chronic Obstructive Pulmonary Disease
Registration Number
NCT01096303
Lead Sponsor
The University of Texas Health Science Center, Houston
Brief Summary

The main hypothesis is that persons that smoke or smoked tobacco and marihuana have worsen lung function as compared with persons that only smoke or smoked tobacco.

Detailed Description

We will follow persons with already diagnosed COPD (chronic bronchitis and/or emphysema). Obtain their smoking history: tobacco and marihuana and review their pulmonary function study results. Then we are planning to compare both groups.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
200
Inclusion Criteria
  • COPD patients former or current tobacco smokers
  • COPD patients former or current tobacco and marihuana smokers
Exclusion Criteria
  • History of COPD without pulmonary function testing
  • Refusal to provide smoking or marihuana used history

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Obstructive limitation in pulmonary function test1 year

Comparison on the severity of obstruction among both groups

Secondary Outcome Measures
NameTimeMethod
Airtrapping1 year

Comparison on the severity of air-trapping by pulmonary function testing among groups.

Decreased diffusion capacity for carbon monoxide1 year

Comparison on the severity of decreased DLco among groups.

Trial Locations

Locations (2)

The University of Texas- Health Science Center at Houston

🇺🇸

Houston, Texas, United States

Lyndon B Johnson General Hospital

🇺🇸

Houston, Texas, United States

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