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Clinical Trials/NCT06507501
NCT06507501
Completed
Not Applicable

Effects of Exercise Training with Blood Flow Restriction on Lower Extremity Muscle Strength, Balance, Functional and Cognitive Performance in Healthy Individuals

Atlas University1 site in 1 country30 target enrollmentApril 15, 2024
ConditionsHealthy

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Healthy
Sponsor
Atlas University
Enrollment
30
Locations
1
Primary Endpoint
Dynamic Balance
Status
Completed
Last Updated
last year

Overview

Brief Summary

In this study, it was aimed to compare the effects of low load blood flow restriction exercise (LL-BFRE) training versus high load resistance exercise (HL-RE) training in healthy young individuals on the parameters of lower extremity muscle strength, dynamic and static postural balance, functional performance and cognitive performance.

Detailed Description

In this randomized controlled study, there will be two study group. Study group 1 will recieve low load blood flow restriction exercise training and Study group 2 will recieve high load resistance exercise training for 6 weeks, 2 exercise sessions weekly. At baseline assessment, individuals who met the inclusion criteria, informed by the researcher and accept the participate in the study, researcher will record the participants' sociodemographic and physical informations and then, asess the lower extremity muscle strength with Hand-held digital dynamometer, dynamic postural balance with Y-Balance Test-Lower Quarter, static postural balance with Single Leg Stance Test (Eyes open/closed condition), functional performance with 6-Minute Walking Test and cognitive performance with Stroop Word and Colour Test and Trail Making Test. At the end of the 6 week exercise training all participants will undergo the same assessments.

Registry
clinicaltrials.gov
Start Date
April 15, 2024
End Date
February 6, 2025
Last Updated
last year
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Atlas University
Responsible Party
Principal Investigator
Principal Investigator

Onur Turan

Research Assisstant

Atlas University

Eligibility Criteria

Inclusion Criteria

  • Volunteering to participate in the study,
  • Being between the ages of 18-30.

Exclusion Criteria

  • Presence of any painful condition or pathology involving the lower extremity and lumbar spine and the presence of a surgical history,
  • Presence of serious malalignment and deformity affecting the lower extremity,
  • Presence of neuromuscular and metabolic disease,
  • Presence of any disease affecting lower extremity circulation,
  • Having a history of deep vein thrombosis and the presence of peripheral vascular disease,
  • Presence of endothelial dysfunction (ED) and any disease that may cause ED,
  • Presence of active infection, cancer and having received radiotherapy / chemotherapy,
  • Continuous use of anticoagulant medication,
  • Having had COVID-19 in the last 3 months or having long COVID syndrome,
  • Presence of a cognitive or mental disorder that would disability to participate in the study,

Outcomes

Primary Outcomes

Dynamic Balance

Time Frame: Baseline to 6 weeks after exercise training

Dynamic balance will be assessed by using Y-Balance Test Lower Extremity.

Static Balance

Time Frame: Baseline to 6 weeks after exercise training

Static balance will be assessed by using Single Leg Stance Test with eyes open and closed.

Muscle Strength

Time Frame: Baseline to 6 weeks after exercise training

Knee extansor and flexor muscle strength will be measured by using Hoggan Scientific; MicroFET2 brand hand-held dynamometer.

Secondary Outcomes

  • Funtional Performance(Baseline to 6 weeks after exercise training)
  • Cognitive Performance(Baseline to 6 weeks after exercise training)

Study Sites (1)

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