Multicenter Evaluation of Children and Young Adults With Genotype Positive Long QT Syndrome
Completed
- Conditions
- Long QT Syndrome
- Registration Number
- NCT01705925
- Lead Sponsor
- Pediatrix
- Brief Summary
The purpose of the study is to provide comprehensive follow-up in patients with Long QT Syndrome (LQTS) and gain additional information regarding genotype-phenotype correlation and effective management and treatment options.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 92
Inclusion Criteria
- Children and/or young adults diagnosed with heterogeneous repolarization disorder who have genotype positive Long QT, or
- Newly diagnosed mutation positive patients with a confirmed test
Exclusion Criteria
- Children who are phenotypically positive with no molecular testing
- Children that are phenotypically positive but genotype negative
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Adverse Cardiac Events on patients with genotype positive LQT1 who have a normal EKG and absence of symptoms, but a molecular confirmation of LQT1. Enrollment is expected to take approximately 5 years. The patients will be followed until they are no longer cared for by a pediatric cardiology facility (typically post-college) or approximately 21 years of age.
- Secondary Outcome Measures
Name Time Method Adverse Cardiac Events on patients with both phenotype and genotype positive. Enrollment is expected to take approximately 5 years. The patients will be followed until they are no longer cared for by a pediatric cardiology facility (typically post-college) or approximately 21 years of age.
Trial Locations
- Locations (1)
Children's Cardiology Associates
🇺🇸Austin, Texas, United States