Basilar Artery International Cooperation Study - BASICS TRIA

BASICS Study Group0 个研究点目标入组 750 人开始时间: 2012年8月1日最近更新: 2020年2月1日

适应症

试验速览

暂无简介。

•Symptoms and signs compatible with ischemia in the basilar artery territory.
•Basilar artery occlusion confirmed by CTA or MRA.
•Age18 or older (i.e., candidates must have had their 18th birthday).
•If IVT is considered as part of BMM, IVT has to be initiated within 4.5 hours of estimated time of basilar artery occlusion.
•Initiation of IA therapy should be feasible within 6 hours of estimated time of BAO.
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range 350
•F.1.3 Elderly (>=65 years) yes
•F.1.3.1 Number of subjects for this age range 350

•Pre-existing dependency with mRankin =3.
•Females of childbearing potential who are known to be pregnant and/or lactating or who have positive pregnancy tests on admission.
•Patients who require hemodialysis or peritoneal dialysis.
•Other serious, advanced, or terminal illness.
•Any other condition that the investigator feels would pose a significant hazard to the patient if IA therapy is initiated.
•Current participation in another research drug treatment protocol (patient cannot start another experimental agent until after 90 days).
•Informed consent is not or cannot be obtained.
•Imaging Exclusion Criteria
•Lesion consistent with hemorrhage of any degree.
•Significant cerebellar mass effect or acute hydrocephalus.
•Bilateral extended brainstem ischemia.

发起方

BASICS Study Group