Cardiac rehabilitation for people with chronic stable angina (ACTIVATE): a randomised controlled trial

niversity of Liverpool0 个研究点目标入组 518 人开始时间: 2021年9月16日最近更新: 2024年9月9日

适应症

试验速览

2024 Protocol article in https://pubmed.ncbi.nlm.nih.gov/38531561/ (added 27/03/2024)

•1. Aged =18 years
•2. Chronic stable angina with at least 2 out of 3 of the following features:
•2.1. Constricting central chest pain
•2.2. Precipitated by exertion or emotional stress
•2.3. Relieved by rest or glyceryl trinitrate spray
•3. Documented coronary artery disease on angiography with =70% stenosis of coronary arteries based on invasive coronary angiography, computerised tomography angiography, or reversible myocardial ischaemia on myocardial perfusion testing
•4. Revascularisation procedures not planned and treated with medical treatments only. Including people with previous MI, or previous revascularisation procedure who may have attended cardiac rehabilitation in the past.

•1. History of myocardial infarction (MI) within the last 12 months on electronic health record search
•2. History of revascularisation procedure within the last 12 months, or planned at the time of study consent
•3. Participation in cardiac rehabilitation programme within the last 12 months, or planned at time of study recruitment
•4. Significant co-morbidities (as deemed by person confirming eligibility) that would limit participation in the exercise based rehabilitation programme
•5. Refractory angina on maximal medical therapy

发起方

niversity of Liverpool