Cardiac rehabilitation for people with chronic stable angina

Not Applicable

Completed

• Conditions: Angina pectoris; Circulatory System; Chronic stable angina

• Registration Number: ISRCTN10054455
• Lead Sponsor: niversity of Liverpool

Brief Summary

2024 Protocol article in https://pubmed.ncbi.nlm.nih.gov/38531561/ (added 27/03/2024)

Detailed Description

Not available

Study Timeline

• Study Start: 2021-09-16
• Study Completion: 2024-08-01
• Last Update Posted: 9 September 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 518

Inclusion Criteria

1. Aged =18 years
2. Chronic stable angina with at least 2 out of 3 of the following features:
2.1. Constricting central chest pain
2.2. Precipitated by exertion or emotional stress
2.3. Relieved by rest or glyceryl trinitrate spray
3. Documented coronary artery disease on angiography with =70% stenosis of coronary arteries based on invasive coronary angiography, computerised tomography angiography, or reversible myocardial ischaemia on myocardial perfusion testing
4. Revascularisation procedures not planned and treated with medical treatments only. Including people with previous MI, or previous revascularisation procedure who may have attended cardiac rehabilitation in the past.

Exclusion Criteria

1. History of myocardial infarction (MI) within the last 12 months on electronic health record search
2. History of revascularisation procedure within the last 12 months, or planned at the time of study consent
3. Participation in cardiac rehabilitation programme within the last 12 months, or planned at time of study recruitment
4. Significant co-morbidities (as deemed by person confirming eligibility) that would limit participation in the exercise based rehabilitation programme
5. Refractory angina on maximal medical therapy

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Physical limitations measured using the UK Version of Seattle Angina Questionnaire (SAQ-7) Physical Limitation domain at baseline, 6, and 12 months

Secondary Outcome Measures

Name	Time	Method
1. Dyspnea measured using the Rose Dyspnea Scale at baseline, 6, and 12 months<br>2. Anxiety and depression measured using the Hospital Anxiety and Depression Scale (HADS) at baseline, 6, and 12 months<br>3. Perceived self-efficacy measured using the Generalised Self-Efficacy scale at baseline, 6, and 12 months<br>4. Physical activity measured with the ActivPAL accelerometer over 7 days at baseline, 6, and 12 months<br>5. Health–related physical activity measured using the International Physical Activity Questionnaire (IPAQ) at baseline, 6, and 12 months<br>6. Exercise capacity measured using the Incremental Shuttle Walk Test at baseline, 6, and 12 months<br>7. Quality of life measured using the EuroQol 5-Dimension 5-Level Quality of Life questionnaire (EQ-5D-5L) at baseline, 6, and 12 months<br>8. Service utilisation measured using the Client Service Receipt Inventory (CSRI) at baseline, 6, and 12 months