NL-OMON50556
Completed
Not Applicable
Fluorescence Molecular Endoscopy and Molecular Fluorescence-guided Surgery of locally advanced rectal cancer using cetuximab-IRDye800CW: a single-center feasibility safety study. - TRACT-II: Fluorescence Endoscopy and Surgery of Rectal Cancer
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Rectal cancer
- Sponsor
- niversitair Medisch Centrum Groningen
- Enrollment
- 13
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •\- Locally advanced rectal cancer, in multi\-disciplinary colorectal oncology
- •meeting agreed on long course neoadjuvant chemoradiotherapy, followed by
- •surgical removal of the primary tumor;
- •\- Age \>\= 18 years;
- •\- Written informed consent.
Exclusion Criteria
- •\- Medical or psychiatric conditions that compromise the patient\*s ability to
- •give informed consent;
- •\- Concurrent uncontrolled medical conditions;
- •\- Pregnancy or breast feeding. A negative pregnancy test must be available for
- •women of childbearing potential (i.e. premenopausal women with intact
- •reproductive organs and women less than two years after menopause);
- •\- Received an investigational drug within 30 days prior to the dose of
- •cetuximab\-IRDye800CW;
- •\- History of infusion reactions to cetuximab or other monoclonal antibodies;
- •\- Had within 6 months prior to enrollment: myocardial infarction,
Outcomes
Primary Outcomes
Not specified
Similar Trials
Completed
Not Applicable
Fluorescence Molecular Endoscopy of locally advanced esophageal carcinoma using bevacizumab-800CW to evaluate dose response after neoadjuvant chemoradiotherapy: a single-center feasibility study.NL-OMON48982niversitair Medisch Centrum Groningen25
Completed
Not Applicable
Molecular fluorescence endoscopy for the detection of (pre)malignant lesions in Barrett*s esophagus using a fluorescent tracer EMI-137 targeting c-Met: a single-center feasibility and safety study.Barrett's Esophagus1001799010017991NL-OMON42946niversitair Medisch Centrum Groningen25
Not yet recruiting
Not Applicable
Autofluorescence endoscopy and spectroscopy for detection of early Barrett's neoplasia: the AFI-III studyNL-OMON34541Academisch Medisch Centrum50
Not yet recruiting
Phase 2
Real time Molecular Fluorescence and Narrow Band Imaging for detection of the Primary Cancer Lesion in Patients with a Metastatis of Unknown Primary Tumor in the Head and Neckcancer of unknown primaryhead & neck cancer10027656NL-OMON54715niversitair Medisch Centrum Groningen35
Not yet recruiting
Not Applicable
Fluorescence Imaging for the Evaluation of Disease Activity in IBD and Rheumatoid Arthritis using the fluorescent tracer OTL38 targeting the folate B receptor: a single-center pilot study.Crohn's diseasereumatoid arthritisulcerative colitis1001796910003816NL-OMON48394niversitair Medisch Centrum Groningen30