NL-OMON48982CompletedNot Applicable
Fluorescence Molecular Endoscopy of locally advanced esophageal carcinoma using bevacizumab-800CW to evaluate dose response after neoadjuvant chemoradiotherapy: a single-center feasibility study. - Fluorescence endoscopy of esophageal carcinoma
Conditions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Enrollment
- 25
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional
Eligibility Criteria
- Ages
- 18 to 99 (—)
Inclusion Criteria
- •- Locally advanced esophageal carcinoma (cT1b-4a N0-3 M0) in multi-disciplinary
- •esophageal oncology meeting agreed on long course neoadjuvant
- •chemoradiotherapy, followed by esophagectomy;
- •- Age >= 18 years;
- •- Written informed consent.
Exclusion Criteria
- •- Patients with psychological diseases or medical issues who are not able to
- •sign informed consent form;
- •Concurrent uncontrolled medical conditions;
- •Pregnancy or breast feeding. A negative pregnancy test must be available for
- •women of childbearing potential (i.e. premenopausal women with intact
- •reproductive organs and women less than two years after menopause);
- •Irradical endoscopic mucosal resection (EMR) or endoscopic submucosal
- •dissection (ESD) of primary tumor prior to start of neoadjuvant
- •chemoradiotherapy
- •Received a different investigational drug within 30 days prior to the dose of
- •bevacizumab-800CW;
- •History of infusion reactions to bevacizumab or other monoclonal antibodies;
Investigators
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