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To prevent discomfort and swelling in neck region after operation under general anaesthesia, inhalation of drug ketamine and ketamine combined with clonidine is given before giving anaesthesia.

Phase 4
Conditions
Health Condition 1: J398- Other specified diseases of upperrespiratory tract
Registration Number
CTRI/2018/10/015915
Lead Sponsor
Indira Gandhi Institute of medical sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

1)physical status ASA 1-2

2)surgery in supine position under general anaesthesia lasting for up to two hours

Exclusion Criteria

1)history of prior sore throat

2)patients using steroids or NSAIDS

3)patient with COPD, Asthma

4)mallampati grade >2

5)patients with >2 attempts of intubation

6)pregnant women

7)patient and/or his/her acceptable representative not willing to provide their voluntary written informed consent for participation in the study

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Postoperative sore throatTimepoint: Sore throat intensity recorded at 4hrs, 8hrs, 12hrs and 24hrs postoperatively
Secondary Outcome Measures
NameTimeMethod
Blood pressure and oxygen saturationTimepoint: Blood pressure and oxygen saturation measured at 4hrs, 8hrs,12hrs and 24hrs postoperatively
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