Comparison of Efficacy of Nebulized Ketamine with Intravenous Morphine in Patients with Multiple Trauma

Phase 2

Recruiting

Conditions: Patients with Multiple Trauma.

Registration Number: IRCT20200602047633N1

Lead Sponsor: Yazd University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: All

Target Recruitment: 200

Inclusion Criteria

Trauma patients with trauma pain with a pain score greater than 4
Age over 4 years
Age less than 65 years

Exclusion Criteria

Patients with level of consciousness 13
Housing consumption in the last 4 hours
History of seizures
Unsatisfied people to participating in the project
Psychedelics and drug addiction
Maxillofacial trauma in which the patient is unable to use a nebulizer mask
Systolic blood pressure less than 90 and more than 180
Respiratory rate less than 10
pulse rate Less than 60 and more than 140
Suspected of bleeding brain lesions or cerebral edema
Pregnancy
History of allergies to any of the drugs used in the study
Frequent nausea and vomiting
Brain Tumor
Glaucoma

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Response to treatment by reducing the pain intensity by two points (20 mm) in terms of visual analog scale (VAS). Timepoint: Measurement of pain score at the beginning of the study (before the intervention) and 5, 10, 15, 30 and 60 minutes after the start of treatment. Method of measurement: visual analog scale (VAS).

Secondary Outcome Measures

Name	Time	Method
Creating analgesia which patient's intensity pain goes below than 5. Timepoint: Measurement of pain score at the beginning of the study (before the intervention) and 5, 10, 15, 30 and 60 minutes after the start of treatment. Method of measurement: visual analog scale (VAS).;Determining the time to start treatment response in two groups. Timepoint: Measurement of pain score at the beginning of the study (before the intervention) and 5, 10, 15, 30 and 60 minutes after the start of treatment. Method of measurement: visual analog scale (VAS).;Determining the frequency of patients who failed treatment in two groups. Timepoint: At the end of the study. Method of measurement: Calculate the number.;Determine the number of times the drug is prescribed. Timepoint: At the end of the study. Method of measurement: Calculate the number.