Prevalence of Two Major Geriatric Syndromes: Sarcopenia and Frailty

Completed

• Conditions: Frailty; Sarcopenia; Frailty Syndrome

• Registration Number: NCT04146844
• Lead Sponsor: Goztepe Training and Research Hospital

Brief Summary

Sarcopenia and frailty are two major syndromes in older adults. They are shown to be associated with low levels of functioning and higher rates of morbidity and mortality. In this study, we aim to report the prevalence of sarcopenia and frailty by using simple assessment methods such as SARC-F and FRAIL, respectively.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2019-10-28
• Study First Submitted QC: 2019-10-30
• Study First Posted: 2019-10-31
• Study Start: 2020-12-15
• Primary Completion: 2021-04-01
• Study Completion: 2021-04-25
• Status Verified: 2021-05
• Last Update Submitted: 2021-05-07
• Last Update Posted: 2021-05-10

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 500

Inclusion Criteria

• Being at the age of 65 or older

Exclusion Criteria

• <24 points on Mini-Mental State Examination
• 12 points or higher on Geriatric Depression Scale

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
FRAIL	5 minutes	The FRAIL scale (Fatigue, Resistance, Ambulation, Illnesses, \& Loss of Weight) is a simple questionnaire of frailty syndrome for older adults. If a patient scores 3-5 points over a total score of 5 points in the FRAIL, he is considered as frail.
SARC-F	5 minutes	SARC-F is a rapid tool to assess sarcopenia in elderly. It is considered indicative sign of sarcopenia if the person scores 4 points or higher out of 10 points.

Secondary Outcome Measures

Name	Time	Method
Mini-Nutritional Assessment (MNA)	10 minutes	Assessment of nutritional status
Mini-Mental State Examination	15 minutes	Mini-Mental State Examination
Study of Osteoporotic Fracture (SOF) Criteria for Frailty	5 minutes	SOF is another index for measuring frailty. 2 or 3 points out of 3 points are considered as cut-off points for frailty.
Charlson Comorbidity Index	5-10 minutes	For comorbidity assessment
Rapid Assessment of Physical Activity (RAPA)	10 minutes	For the assessment of physical activity level
Katz Index of Independence in Activities of Daily Living	10 minutes	Assessment of activities of daily living
Blood Sample Analysis	5 minutes	A blood sample analysis will be performed to investigate the relationship between blood parameters, sarcopenia and frailty.
Geriatric Depression Scale- Short Form	10 minutes	Assessment of depression
Lawton -Brody Instrumental Activities of Daily Living Scale	10 minutes	Instrumental activities of daily living assessment

Trial Locations

Locations (1)

Umraniye Education and Research Hospital; 🇹🇷 Istanbul, Turkey