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Optimization of Initial Energy for Cardioversion of Atrial Fibrillation With Biphasic Shocks

Not Applicable
Conditions
Atrial Fibrillation
Cardioversion
Interventions
Procedure: 100 joule as first biphasic shock energy
Procedure: 120 joule as first biphasic shock energy
Registration Number
NCT01910779
Lead Sponsor
Maria Vittoria Hospital
Brief Summary

Use of higher energy doses (120-150 J) may not offer additional benefits and higher success rate compared with low to moderate initial energy (100-120 J) of biphasic shock for atrial fibrillation cardioversion. In this prospective open-label randomized trial consecutive patients with AF and candidate to AF electrical cardioversion will be randomized to receive 100J or 120 J as initial dose of biphasic shock. Patients will be also randomized in each group to anterolateral or postero-anteriore placement of defibrillator electrodes.

Detailed Description

Open-label randomized trial to assess the efficacy of alternative initial biphasic shocks (100 versus 120 J) for cardioversion of atrial fibrillation including alternative option for electrode placement (anterolateral or postero-anterior in each group).

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
154
Inclusion Criteria
  • Adult (Age>18 years)
  • Candidate to Cardioversion for recent onset, persistent atrial fibrillation (>48 hours but < 12 months)
  • Informed Consent
Exclusion Criteria
  • Atrial Flutter or other arrythmias

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
100 joule arm100 joule as first biphasic shock energy100 joule as first biphasic shock energy
120 joule arm120 joule as first biphasic shock energy120 joule as first biphasic shock energy
Primary Outcome Measures
NameTimeMethod
Electrical cardioversion successDay 1
Secondary Outcome Measures
NameTimeMethod
Electrical cardioversion success3 months
Complications rateDay 1

Trial Locations

Locations (1)

Cardiology Dpt. Maria Vittoria Hospital

🇮🇹

Torino, Italy

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