Assessment Of Vaitarana Basti And Rasna Guggulu In The Management Of Pain In Gridhrasi (Sciatica) A Randomized Controlled Clinico Experimental Study
Trial Snapshot
- Phase
- Phase 3
- Status
- Completed
- Sponsor
- Enrollment
- 90
- Locations
- 1
- Primary Endpoint
- Assessment will be done on the basis of special designed proforma
Study Overview
Brief Summary
This study was a randomized, parallel group, activecontrolled trial comparing the safety and efficacy of Vaitarana Basti(16 days) and Rasna guggulu 1gms/day (30 days), Vaitarana basti(16 days) and Rasna guggulu 1 gms/day (30 days) in 101 patients withSciatica that was conducted in Panchakarma Hospital, IPGT&RA, GujaratAyurveda University, Jamnagar. The primary outcome measures were assessed onthe basis of relief found in the cardinal features of the disease. Pain by VisualAnalogue Scale, Stambha (stiffness), Suptata (numbness), Spandana(throbbing/pulsating), Aruchi (anorexia), Tandra (drowsiness), Gaurava(heaviness) muscle power and Straight Leg Raising are the criteria’s which was assessedaccording to their respective standard grading’s before treatment, aftertreatment and after follow up period of 4 weeks.
A total of 101 patients were enrolledfor the study and allotted to three groups by randomization sequence. From thissample 96 patients completed the study and 5 patients discontinued due topersonal reasons. The main findings of the study were: Vaitarana Basti is more effective in managing Vata Kaphatype of Gridhrasi while Rasna guggulu is better for Vatikatype of Gridhrasi. Upon the assessment on effect of therapies, combinedeffect of Vaitarana basti and Rasna guggulu provided best resultsin comparison to Vaitarana Basti and Rasna guggulu givenseparately. Vaitarana basti gave better results than Rasna gugguluin individual administration of medicines.
Study Design
- Study Type
- Interventional
- Allocation
- Computer generated randomization
- Masking
- Open Label
Eligibility Criteria
- Ages
- 20.00 Year(s) to 65.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •Diagnosed cases of Gridhrasi with symptoms like Ruja, Stambha, Suptata, Spandana, Tandra, Gaurava, Arochaka.
- •Patients of age group between 20 and 65 years, belonging to both sex.
- •Patients indicated for basti karma Willing to sign the consent for study participation.
Exclusion Criteria
- •Uncontrolled diabetes mellitus, hypertension, tuberculosis of spine and hip joint, malignancy of spine or other organs Fracture related to spine Cardiac diseases (ischemic heart disease, coronary artery disease, myocardial infarction etc.) Anemia (hemoglobin % <07.00 mg/dl) Pregnancy.
- •Patients contraindicated for basti.
Outcomes
Primary Outcomes
Assessment will be done on the basis of special designed proforma
Time Frame: 7 days
Secondary Outcomes
- Assessment will be done on the basis of special designed proforma(60 days)