Evaluation of the effect of using local anesthetics inside the endotracheal tube cuff on emergence reactions from anesthesia

Phase 3

Recruiting

• Conditions: T88.9XXA; Cough, sore throat, and hoarseness after extubation.; Complication of surgical and medical care, unspecified, initial encounter

• Registration Number: IRCT20120910010800N4
• Lead Sponsor: Shahid Beheshti University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 2 May 2022

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 350

Inclusion Criteria

Age older than 18 years old
Consent to the study
Performing general anesthesia using endotracheal intubation

Exclusion Criteria

Drug abuse
Existence of uncontrolled underlying disease
Pre-existing sore throat
Pre-existing hoarseness
Pre-existing cough
Recent respiratory infection
History of hyperactive airways
History of prolonged intubation
Anticipated difficult intubation
Risk of aspiration of gastric contents

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Cough. Timepoint: At zero, ten minutes, thirty minutes, 6 hours, and 24 hours after extubation. Method of measurement: Anesthesiologist observation to determine its presence and severity (mild: less than 5 coughs, moderate: more than 5 coughs, severe: frequent coughs that prevent the patient from breathing normally).;Sore throat. Timepoint: At zero, ten minutes, thirty minutes, 6 hours, and 24 hours after extubation. Method of measurement: Patient self-reported based on either three, moderate, or severe levels.;Hoarseness. Timepoint: At zero, ten minutes, thirty minutes, 6 hours, and 24 hours after extubation. Method of measurement: Observe an anesthesiologist by determining its presence and severity (mild: ability to speak easily with slight change in voice, moderate: difficulty speaking, severe: complete hoarseness).