ICU Stay in Patients With Low Ejection Fraction Undergoing Cardiac Revascularization: Comparison of On-pump vs Off-pump Coronary Artery Bypass Grafting
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Cardiac Revascularization
- Sponsor
- Armed Forces Institute of Cardiology, Pakistan
- Enrollment
- 60
- Locations
- 1
- Primary Endpoint
- ICU Stay
- Status
- Completed
- Last Updated
- 5 years ago
Overview
Brief Summary
Coronary artery bypass graft (CABG) surgery can result in severe postoperative complications, such as renal and pulmonary failure. In about 80% of the cases worldwide, it is currently performed with cardiopulmonary bypass (CPB) with cardiac arrest. Cardiopulmonary bypass leads to a systemic inflammatory response, which may be induced by the contact of circulating blood with artificial surfaces of the extracorporeal circuit.[1] To reduce postoperative complications caused by systemic inflammation, off-pump CABG was reintroduced into clinical practice in the early 1990s. During off-pump surgery, the coronary artery grafts are placed on coronaries of a beating heart, thereby avoiding aortic cross clamping and CPB. [1] There are many studies and debates about the two approaches to cardiac revascularization via CABG. This study aims to answer the question as to difference in the ICU stay of patients with low ejection fraction undergoing cardiac revascularization bet ween off pump and on pump coronary artery bypass grafting and better treatment option shall be adopted in future.
Investigators
Muhammad Bilal
Cardiac Surgeon
Armed Forces Institute of Cardiology, Pakistan
Eligibility Criteria
Inclusion Criteria
- •All patients of either gender between the ages of 40 to 80
- •Ejection fraction of less than or equal to 35% undergoing CABG.
- •undergoing CABG.
Exclusion Criteria
- •Patients with ejection fraction of more than 35%
- •Patients with previous history of cardiac revascularization
- •Patients with previous history of chronic kidney disease and obstructive sleep apnea.
Outcomes
Primary Outcomes
ICU Stay
Time Frame: 6 Months
post operative ICU stay in patients undergoing cardiac revascularization