Prospective study on the relevance of the detection of respiratory viruses in pharyngeal aspirates in healthy individuals
- Conditions
- Healthy VolunteerJ00-J06Acute upper respiratory infections
- Registration Number
- DRKS00005367
- Lead Sponsor
- niversitätsklinikum Jena
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 273
Inclusion Criteria
>17 years of age
- written informed consent
Exclusion Criteria
- no informed consent
- pulmonary disease of any kind with or without medication
-Disease that leads to immunosuppression at study entry or within the past 5 years including diabetes mellitus
-immunosuppressive or immunemodulating medication at study entry or within the past 5 years
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method prevalence of positive results for viral pathogens in pharyngeal aspirates from healthy donors determined by multiplex PCR at timepoint 0, 3 weeks later and at the onset of an acute respiratory infection
- Secondary Outcome Measures
Name Time Method correlation of positive results for viral pathogens determined by PCR with symptoms, stress level and smoking at timepoint 0, 3 weeks later and at the onset of an acute respiratory infection