A Randomized Controlled Trial for Qing Jin Yi Qi granule in the treatment of Convalescence Patients of Novel Coronavirus Pneumonia(COVID-19)
- Conditions
- ovel Coronavirus Pneumonia (COVID-19)
- Registration Number
- ITMCTR2100004379
- Lead Sponsor
- Shijiazhuang People's Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- Not specified
1) Conform to the diagnostic criteria of COVID-19(Guidelines for the diagnosis and treatment of coronavirus disease 2020(trial version eighth))Patients who met the discharge standard and had negative neocoronavirus nucleic acid detection after discharge
2) Aged 18-75 years;
3) Having clinical manifestations of respiratory symptoms or fatigue;
4) Patient informed consent.
1) Patients who have undergone operations that affect lung function, such as lung transplantation, lung resection, lung volume reduction, etc;
2) Dependent on mechanical ventilation to maintain lung function, such as ventilator;
3) Combined with chronic lung diseases that affect lung function, such as severe chronic obstructive pulmonary disease;
4) Patients with heart function related diseases, such as heart failure and pacemaker installation;
5) Severe underlying diseases affecting survival, including uncontrolled heart, kidney, digestive, blood diseases, neuropsychiatric diseases, immune diseases, metabolic diseases, malignant tumors, severe malnutrition, etc;
6) Resting heart rate > 120 / min;
7) Systolic blood pressure > 180mmhg, diastolic blood pressure > 100mmhg;
8) Unstable angina pectoris or myocardial infarction in recent 1 month;
9) Severe obesity (BMI > 30 kg / m2);
10) Allergic constitution, allergic to the drug components involved in the treatment program;
11) Pregnant or lactating women;
12) Disabled people who can't complete the collection of efficacy evaluation indicators;
13) Mental state can not cooperate, suffering from mental illness, no self-control, can not express clearly;
14) Participants in other clinical trials;
15) According to the judgment of the researchers, there will be patients with complications or poor compliance that affect the efficacy and safety evaluation.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method modified Medical Research Council Dyspnea Scale (MMRC);Borg perceived fatigue scale;Visual analogue scale for cough;
- Secondary Outcome Measures
Name Time Method 6 minutes walking distance;Blood oxygen saturation;Immune inflammation index;Depression Scale (PHQ-9), anxiety scale (GAD-7);Chest CT;TCM syndrome score;