Exercise therapy intervention for children and young adults with cerebral palsy

Not Applicable

Completed

• Conditions: Nervous System Diseases; Cerebral Palsy; Cerebral palsy

• Registration Number: ISRCTN69044459
• Lead Sponsor: niversity of Jyväskylä

Brief Summary

2021 Protocol article in https://pubmed.ncbi.nlm.nih.gov/33637124/ protocol (added 01/03/2021) 2022 Interim results article in https://doi.org/10.3389%2Ffbioe.2022.897852 (added 12/12/2022) 2023 Results article in https://doi.org/10.1249/MSS.0000000000003273 (added 18/09/2023) 2022 Results article in https://doi.org/10.3389/fbioe.2022.897852 (added 18/09/2023)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2017-04-21
• Study Completion: 2023-01-31
• Last Update Posted: 23 October 2023

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 36

Inclusion Criteria

Current participant inclusion criteria as of 20/06/2019:
Experimental group:
1. Spastic CP (diplegic or hemiplegic)
2. Male and Female
3. Age range of 9 to 24 years old
4. Gross Motor Function Classification System (Palisano et al. 2008) levels 1 to 3

Control group:
1. Typically developing
2. Male and Female
3. Age range of 9 to 24 years old

Previous participant inclusion criteria:
Experimental group:
1. Spastic CP (diplegic or hemiplegic)
2. Male and Female
3. Age range of 10 to 23 years old
4. Gross Motor Function Classification System (Palisano et al. 2008) levels 1 to 3

Control group:
1. Typically developing
2. Male and Female
3. Age range of 10 to 23 years old

Exclusion Criteria

1. Pharmacological treatments (e.g. intrathecal baclofen, botullinum toxin) in the last 6 months
2. Surgical procedures in the last 6 months
3. Selective dorsal rhyzotomy
4. Dystonia
5. Inability to understand basic instructions
6. Current utilization of serial casting
7. Inability to stand with the sole of the foot flat on the floor
8. Participation in the past 3 months in a structured physical training program

*Exclusion criteria 1 to 3 may be accepted as a case study (added 20/06/2019).

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<br> Current primary outcome measure as of 20/06/2019:<br> Gait performance is assessed using a six minute walking test. Gait kinetics/kinematics/mechanical efficiency is assessed using Vicon cameras, force plates and a heart rate monitor at pre-tests 1 and 2, and post-tests 1 and 2 for the CP group and pre-tests 1 and 2 for the control group.<br><br> Previous primary outcome measure:<br> Gait performance is assessed using a 6 minutes walking test at baseline (pre-test 1), 3 (pre-test 2), 6 (post-test 1) and 9 (post-test 2) months for participants with CP and at baseline and 3 months for control participants.<br>