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临床试验/NCT06209073
NCT06209073尚未招募不适用

Efficacy of Virtual Reality Exercises on Sarcopenia in Patients With Liver Transplantation

Cairo University1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2024年1月25日最近更新:
适应症

试验速览

阶段
不适用
状态
尚未招募
入组人数
60
试验地点
1
主要终点
Hand grip strength

研究概览

简要总结

This study will be conducted to investigate the effect of virtual reality exercises on hand grip strength, pinch strength, quadriceps muscle strength, exercise capacity, fatigue, and quality of life in patients with liver transplantation.

详细描述

Liver transplantation (LT) continues to prove to be the best choice for curing patients with end-stage liver disease (ESLD) . Management strategies in peri-transplantation care have significantly improved the outcomes of patients after LT. One of the most challenging tasks of LT is defining which patients are clinically appropriate for this therapy. Evaluating disease severity for patients with ESLD is a serious challenge for liver transplant surgeons, and there is a critical need for better methods of risk stratification. The most common complications involved include ascites, hepatic encephalopathy, and variceal bleeding; however, severe muscle wasting or sarcopenia is the most common and frequently undiagnosed complications that negatively impact survival, quality of life, and response to stressors, such as infections and surgeries. Virtual reality (VR) is an interactive, 3-dimensional computer experience occurring in real time. It allows the users to participate in multisensory and multidimensional virtual environments . It provides the participants with real-time auditory, visual, and proprioception sensory feedback. It also provides a safe virtual exercise environment. sixty patients with liver transplantation will be assigned randomly to two groups; experimental group will receive virtual reality exercise plus traditional therapy for six weeks, control group will receive traditional therapy alone for six weeks

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Double (Investigator, Outcomes Assessor)

盲法说明

opaque sealed envelop

入排标准

年龄范围
18 Years 至 65 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Sixty patients suffer from sarcopenia with liver transplantation. The age of patients ranges from (18:65) years. All patients must be conscious. Patients suffer from muscle weakness Patients suffer from fatigue Patients with low muscle endurance Patients' cases must be stable to deal with them

排除标准

  • Patients will be excluded if they have any of the following:
  • Any sign of acute rejection of the transplanted organ Acute hemorrhage Electrolyte imbalance Physiological instability Sever neurologic complication Sever cardiovascular co-morbidities

结局指标

主要结局

Hand grip strength

时间窗: up to six weeks

JAMAR hand grip dynamometer will be used to measure hand grip strength

次要结局

  • Respiratory function(up to six weeks)
  • Fatigue(up to six weeks)
  • exercise capacity(up to six weeks)
  • Pinch strength(up to six weeks)
  • life disability(up to six weeks)
  • quadriceps strength(up to six weeks)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Nabil Mahmoud Ismail Abdel-Aal

Principal Investigator: nabil mahmoud ismail abdel-Aal

Cairo University

研究点 (1)

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