Comparative effects of flaxseed oil and vitamin E on non-invasive markers of liver in patients with nonalcoholic fatty liver disease.
- Conditions
- onalcoholic fatty liver.Nonalcoholic fatty liver disease
- Registration Number
- IRCT2013111715427N1
- Lead Sponsor
- Vice Chancellor for research of Mashhad University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 60
The major inclusion criteria are:
The enzyme Aspartate Aminotransferase (AST) and Alanine Aminotransferase (ALT) at least 1.5 times above the normal limit, confirmed by the kidney sonography; Meeting at least one of the following criteria: Within the age range of 15-60 years old, diabetes, Hyperlipidemia, and Obesity.
The major exclusion criteria are as follows:
Consuming alcohol or having a history of drinking problems; Positive serology for viral hepatitis (C , B); Positive Anti-Nuclear Antibody (ANA) or Anti-Mitochondrial Antibodies (AMA) tests, Alpha-1 antitrypsin; Reduced serum levels of ceruloplasmin or increasing levels of Anti-smooth muscle (ASMA) and Liver kidney microsomal type 1 antibody (LKM1) antibodies; Ferritin level larger than 450, or Iron and Total iron binding capacity IRON/TIBC less than 45%; The patients being diagnosed with acute or chronic illnesses which cause disorders in LFT (liver function tests), before or during the medical intervention; the patients’ consumption of drugs, before or during the medical intervention, which cause disorders in LFT; Pregnancy; Age less than 15 or above 60 years.
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method iver Enzyme. Timepoint: Admission and 2 months after applying the intervention. Method of measurement: Blood Sampling.
- Secondary Outcome Measures
Name Time Method Blood Glucose. Timepoint: Admission and 2 months after applying the intervention. Method of measurement: Blood Sampling.